GHK-Cu

Cosmetic

Copper binding tripeptide

Last updated 29 October 2026

A copper binding tripeptide used in topical skincare. Applied to the skin with no medicinal claims it is regulated as a cosmetic. Injectable GHK-Cu, or any version sold with medicinal claims, is an unlicensed medicine.

Key points

  • GHK-Cu is a small peptide that binds copper and occurs naturally in the body.
  • In skincare, used on the skin with no medicinal claims, it is regulated as a cosmetic.
  • Injectable GHK-Cu, or any version sold with medicinal claims, is an unlicensed medicine with no UK marketing authorisation.
  • The skincare evidence is modest, and evidence for injection is limited.

Quick facts

In skincare
Legal as a cosmetic ingredient with no medicinal claims
Injected
Unlicensed as a medicine; no UK marketing authorisation
Class
Copper binding tripeptide
Evidence
Some topical studies; limited data for injection

How it works

In skin, GHK-Cu is thought to support collagen and the skin's natural repair processes, which is why it appears in some cosmetic products. Most of the evidence relates to topical use rather than injection.

What the evidence shows

There are some studies of GHK-Cu in topical skincare. Evidence for injected use is limited, and cosmetic benefits are best treated as modest.

What it does not settle

  • Injected use is not well studied in people.
  • Cosmetic claims should be kept modest and not medicinal.

UK legal status and access

As a topical cosmetic with no medicinal claims, GHK-Cu is legal and widely sold. Injectable GHK-Cu, or any version sold with medicinal claims, is an unlicensed medicine and is not available through regulated providers.

Common questions

Is GHK-Cu legal in the UK?

In skincare, with no medicinal claims, yes, as a cosmetic ingredient. Injectable or medicinal versions are unlicensed medicines.

What is the difference between the cream and the injection?

A topical cosmetic is regulated under cosmetics rules. An injectable product, or one sold with medicinal claims, falls under medicines rules and has no UK marketing authorisation.

Factual reference only, not medical advice. We give no dosing for unlicensed compounds.

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GHK-Cu · UK legal status · On the Register