DSIP

Key points

• DSIP is a short natural peptide found in the brain and blood.
• It is marketed to promote deep sleep and to help with stress.
• The evidence behind these claims is limited, and how it works is not well understood.
• It is not a licensed medicine in the UK and is sold only for research use.

Quick facts

What it is

Delta sleep inducing peptide (natural brain peptide)

Marketed for

Sleep and stress

UK status

Not a licensed medicine; sold for research use

Evidence

Weak; old and limited research

How it works

DSIP is named for an early link to deep, slow wave sleep, and it is also suggested to influence stress hormones. The exact pathways are not well defined, and the effects of giving it as a treatment, rather than the small amounts the body makes, are unclear.

What the evidence shows

There is little good evidence for DSIP as a sleep or stress treatment. The research is old and limited, with no modern controlled trials of the kind needed to support these claims or to license a medicine.

What it does not settle

• There is little reliable evidence that it improves sleep or stress in people.
• There is no established dose or clear safety picture.
• How it behaves when given, rather than made naturally, is poorly understood.

Side effects

Less common but serious

• Human safety data is limited, so the risks are not well characterised.
• Because there is no licensed product, the dose, purity and contents of material bought online cannot be verified.

Report any suspected side effect through the MHRA Yellow Card scheme.

UK legal status and access

DSIP has no UK marketing authorisation, so it is not a licensed medicine and is not offered by registered clinics or pharmacies. It is sold online for research use.

Common questions